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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

Fig. 5

MMP and TIMP responses of LACV infected neuron/astrocyte co-cultures. Neuron/astrocyte co-cultures were either mock infected, treated with inactivated LACV, treated with Poly I:C, or infected with 0.1, 1, 10 MOI of LACV. a RNA was collected and analyzed via qRT-PCR against selected MMPs and TIMPs. Values are reported as fold change relative to mock treatment normalized to 18S RNA. b MMP activity assays were performed to determine MMP cleavage activity. *P < 0.5, **P < 0.01

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