Fig. 1

Diminished mechanical hyperalgesia, edema, and arthritis severity score, but retained grasping ability after sensory desensitization. The changes of the hind paw mechanonociceptive threshold (a), grasping ability (b), hind limb edema (c), and the semiquantitative arthritis severity score (d). Values are the means ± SEM, n = 7–8/group. *p < 0.05, ***p < 0.001 vs. respective non-arthritic controls, ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs. non-desensitized arthritic mice. Grasping ability was assessed by log rank test, all other functional results by repeated measures two-way ANOVA