Fig. 2

Lcn2 production is increased in the J20 brain, and is localized in GFAP-positive astrocytes. a Representative images of fluorescent staining for Lcn2 in the hippocampus of WT, J20, Lcn2 KO, and J20xLcn2 KO mice. b Representative images of fluorescent co-staining for Lcn2 and the neuronal marker NeuN, in the J20 hippocampus. c Representative images of fluorescent co-staining for Lcn2 and the microglia marker Iba1, in the J20 hippocampus. d Representative images of fluorescent co-staining for Lcn2 and the astrocyte marker GFAP, in the J20 hippocampus. Images were acquired with a 63x (oil) objective lens. Scale bar: 25 μm