Fig. 5

Increased fractalkine receptor protein level in the contralateral thalamus only 14 days after spinal nerve ligation. Western blot (A1 and B1) and densitometric analysis (A2 and B2) were performed on contralateral thalamic protein extracts from naïve (n = 4), sham (n = 5), and SNL (n = 6) animals 14 (A1 and A2) or 28 (B1 and B2) days after the beginning of the experiments. CX3CR1 (fractalkine receptor) protein level is significantly increased in SNL animals compared to naïve rats 14 days after the beginning of the experiment (A2: one-way ANOVA F(2, 12) = 7.877, p = 0.0065) while no significant difference is found 28 days after the beginning of the experiment (B2: one-way ANOVA F(2, 12) = 1.645, p = 0.2336). Post hoc test (Tukey’s multiple comparison test): **p < 0.01