Fig. 3

Behavioral outcomes after treatment with MSCs + IL-10. a Mean latency to find the platform in the MWM task across 4 days with platform in the northeast (NE) quadrant, all TBI groups took a significantly longer time to find the target platform than the sham + vehicle group (***p < 0.001). b Reversal trials with the platform in the southwest (SW) quadrant (mean latency across 3 days) indicated sham + vehicle group was significantly faster in finding the platform than TBI + vehicle (*p < 0.05) and TBI + MSCs (**p < 0.01) but not TBI + MSCs + IL-10. c Mean number of foot faults in the ladder rung walking task. Ladder rung test was run once a week for 3 weeks. TBI + vehicle group had significantly more foot faults than all other groups (*p < 0.05, ***p < 0.001), and the sham + vehicle group had significantly fewer foot faults than all other groups (##p < 0.01). d Mean latency (sec) to remain on the rotating rod in the rotarod test. The rotarod test was performed for 5 days, 4 trials per day. An injury effect was observed in TBI groups, whereas sham + vehicle group stayed on the rod significantly longer time than all other groups (**p < 0.01, ***p < 0.001). Error bars represent ± SEM