Fig. 4

Loss of Par1b/MARK2 increases microglia phagocytosis during postnatal development. a Representative 3D surface renderings of individual microglia (green) with engulfed neuronal particles (neurofilament, blue; synapsin1, red) from the parietal association cortex. b Quantifications of neuronal material phagocytized within each microglia. Par1b (−/−) microglia were found to engulf more neuronal particles than Par1b (+/+), n (animals/microglia) = Par1b (−/−): (2/34); Par1b (+/−): (7/44); Par1b (+/+) (6/39), *p < 0.05 by one-way ANOVA