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Table 3 Comparing group levels of CSF YKL-40, neopterin, and NFL using Tukey’s multiple comparison test after one-way ANOVA

From: Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection

Group comparisons CSF YKL-40 (log) CSF neopterin (log) CSF NFL (log)
Overall ANOVA p
< 0.0001 < 0.0001 < 0.0001
Tukey’s multiple comparison
 HAD vs. HIV– < 0.0001 ND < 0.0001
 HAD vs. ART < 0.0001 < 0.0001 < 0.0001
 HAD vs. NA CD4 ≥ 350 < 0.0001 < 0.0001 < 0.0001
 HAD vs. NA CD4 200–349 < 0.0001 ns < 0.0001
 HAD vs. NA CD4 50–199 < 0.0001 ns < 0.0001
 HAD vs. NA CD4 < 50 < 0.0001 ns < 0.0001
 NA CD4 < 50 vs. HIV– < 0.0001 ND < 0.0001
 NA CD4 < 50 vs. ART < 0.05 < 0.0001 < 0.0001
 NA CD4 < 50 vs. NA CD4 ≥ 350 < 0.05 < 0.0001 < 0.0001
 NA CD4 < 50 vs. NA CD4 200–349 ns ns < 0.0001
 NA CD4 < 50 vs. NA CD4 50–199 ns ns ns
 NA CD4 50–199 vs. HIV– < 0.0001 ND ns
 NA CD4 50–199 vs. ART ns < 0.0001 < 0.05
 NA CD4 50–199 vs. NA CD4 ≥ 350 ns < 0.01 ns
 NA CD4 50–199 vs. NA CD4 200–349 ns ns ns
 NA CD4 200–349 vs. HIV– < 0.05 ND ns
 NA CD4 200–349 vs. ART ns < 0.0001 ns
 NA CD4 200–349 vs. NA CD4 ≥ 350 ns < 0.05 ns
 NA CD4 ≥ 350 vs. HIV– ns ND ns
 NA CD4 ≥ 350 vs. ART ns < 0.01 ns
 ART vs. HIV– ns ND ns
  1. Median cerebrospinal (CSF) levels of YKL-40, neopterin, and NFL for the different groups
  2. IQR interquartile range, ND no data, ns not significant, NA neuroasymptomatic, HAD HIV-associated dementia, ART antiretroviral therapy