Fig. 5

CXCL10 and CXCL12 levels in placenta. CXCL10 levels in placental tissue, measured by ELISA, were increased by polyI:C administration in placentae from Map2k7 Hz dams but not WT dams, irrespective of the embryonic genotype (a). Conversely, CXCL12 levels were increased by polyI:C administration in placentae from WT dams but not Map2k7 Hz dams in placental tissue, again irrespective of the embryonic genotype (b). Results shown are mean ± SEM, N = 4–7/group. ^#p < 0.05, ^##p < 0.01 as shown, *p < 0.05, **p < 0.01 vs vehicle-treated group, same dam and embryo genotype (post-hoc Fisher’s test); F values are provided in the Additional file 1