Fig. 9

ATF4 inactivation specifically in oligodendrocytes did not affect T cell priming in the peripheral immune system during EAE. a The MTT cell viability assay showed that ATF4 inactivation specifically in oligodendrocytes did not significantly alter T cell viability in response to MOG35–55 peptide. b BrdU cell proliferation assay showed that ATF4 inactivation specifically in oligodendrocytes did not significantly alter T cell proliferation in response to MOG35–55 peptide. c–e ELISA analyses showed that ATF4 inactivation specifically in oligodendrocytes did not significantly affect the ability of T cells to produce the cytokines IFN-γ, IL-4, or IL-17A in response to MOG35–55 peptide. N = 3 animals. Error bars represent SD. n.s. not significant