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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE

Fig. 9

ATF4 inactivation specifically in oligodendrocytes did not affect T cell priming in the peripheral immune system during EAE. a The MTT cell viability assay showed that ATF4 inactivation specifically in oligodendrocytes did not significantly alter T cell viability in response to MOG35–55 peptide. b BrdU cell proliferation assay showed that ATF4 inactivation specifically in oligodendrocytes did not significantly alter T cell proliferation in response to MOG35–55 peptide. ce ELISA analyses showed that ATF4 inactivation specifically in oligodendrocytes did not significantly affect the ability of T cells to produce the cytokines IFN-γ, IL-4, or IL-17A in response to MOG35–55 peptide. N = 3 animals. Error bars represent SD. n.s. not significant

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