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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance

Fig. 6

A schematic diagram. SFO Iba1+ perivascular macrophages expressed IL-1β 1 h after the first dose of peripheral LPS injection (first LPS challenge). Four days after the first injection, mice became endotoxin-tolerant. Bone marrow-derived perivascular macrophages accumulated in the SFO and did not express IL-1β after the second dose of LPS (tolerance established)

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Journal of Neuroinflammation

ISSN: 1742-2094