Genetic variability of inflammation and oxidative stress genes does not play a major role in the occurrence of adverse events of dopaminergic treatment in Parkinson’s disease

Table 5 Results of the multivariate logistic regression

Association		OR adj.^a	95% CI	p value
SNP	Adverse event	OR adj.^a	95% CI	p value
NOS1 rs2682826	EDS and sleep attacks	1.75	1.00–3.06	0.048
SOD2 rs4880	Nausea/vomiting	0.49	0.25–0.94	0.031
IL1β rs1143623	Orthostatic hypotension	0.57	0.32–0.99	0.050
CAT rs1001179	Peripheral edema	0.32	0.15–0.68	0.003
NOS1 rs2682826	Impulse control disorders	2.59	1.09–6.19	0.032

^aHomozygotes for wild-type allele were used as reference. Adjustments are stated in the text
Significant and nominally significant results are written in bold text

ISSN: 1742-2094