Fig. 1
Representative clinical course of EAN rats. a. EAN was induced in Lewis rats by immunization on day 0 with P253–78 peptide plus CFA. Rats received human triamcinolone (TRIAM) intrathecally at doses of 0.3 mg/kg and 0.6 mg/kg on day 11 p.i. Control rats received NaCl 0.9% only. The experiment was repeated two times, each time with n = 5/group. Mean values and SEM are depicted. Statistical analysis and p value calculation were performed calculating the area under the curve (AUC). b Comparison of AUC was done using one-way ANOVA combined with Tukey’s multiple comparisons test. Mean values and SD are depicted (NaCl-treated vs 0.6 mg/kg; **p < 0.001, n = 5)