Table 1 Baseline characteristics of the included and excluded study participants
Characteristic | Included participants (N = 8313) | Excluded participants (N = 1528)# | |
|---|---|---|---|
No blood measurements (N = 1288) | Unknown APOE genotype (N = 240) | ||
Age, year, mean (SD) | 61.1 (7.4) | 72.6 (11.8) | 61.7 (8.2) |
Women | 4729 (56.9) | 845 (65.6) | 160 (66.7) |
Education | |||
Primary | 908 (11.0) | 233 (18.4) | 25 (11.7) |
Lower | 3329 (40.3) | 537 (42.4) | 95 (44.4) |
Intermediate | 2429 (29.4) | 336 (26.5) | 57 (26.7) |
Higher | 1588 (19.2) | 161 (12.7) | 37 (17.3) |
Body mass index, kg/m2, mean (SD) | 27.6 (4.3) | 27.6 (4.5) | 28.2 (4.8) |
Smoking status | |||
Current | 1595 (19.3) | 308 (24.4) | 57 (24.5) |
Former | 4191 (50.7) | 550 (43.6) | 106 (45.5) |
Diabetes mellitus | 501 (6.0) | 136 (10.7) | 15 (6.3) |
History of stroke | 305 (3.7) | 54 (4.2) | 11 (4.6) |
APOE ε4 carrier status | 2328 (28.0) | 244 (30.8) | |
Blood cell types, 109/L, median (IQR) | |||
Granulocytes | 3.8 (1.6) | 4.0 (1.7) | |
Platelets | 263 (84) | 277 (87) | |
Lymphocytes | 2.2 (0.8) | 2.3 (0.9) | |
Blood cell-based ratios, median (IQR) | |||
Granulocyte-to-lymphocyte ratio | 1.7 (0.9) | 1.7 (0.8) | |
Platelet-to-lymphocyte ratio | 120 (55) | 119 (54) | |
Systemic immune-inflammation index | 455 (280) | 473 (312) | |