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Table 2 Frequencies of KIR haplotypes and HLA alleles among individuals acute ischemic stroke and in subjects without stroke

From: HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute ischemic stroke

Aplotipo KIR

Subjects with acute ischemic stroke (n 116)

Subjects without acute ischemic stroke (n 66)

p

2DL1 (n/%)

64 (55.17)

43 (65.16)

0.21

2DL2 (n/%)

41 (35.34)

26 (39.3)

0.63

2DL3 (n/%)

86 (74.1)

28 (42.4)

< 0.0001

2DL4 (n/%)

84 (72.4)

66 (100)

< 0.0001

2DL5A (n/%)

14 (12.06)

12 (18.8)

0.27

2DL5B (n/%)

39 (33.6)

12 (18.8)

0.03

2DS1 (n/%)

24 (20.6)

18 (27.2)

0.36

2DS2 (n/%)

44 (37.9)

11 (16.6)

0.003

2DS3 (n/%)

31 (26.7)

17 (25.7)

1

2DS4 (n/%)

48 (41.3)

11 (16.6)

0.001

2DS5 (n/%)

17 (14.6)

34 (51.5)

< 0.0001

3DL1 (n/%)

78 (67.2)

59 (89.3)

0.001

3DL2 (n/%)

78 (67.2)

66 (100)

< 0.0001

3DL3 (n/%)

73 (62.9)

66 (100)

< 0.0001

3DS1 (n/%)

60 (51.7)

37 (56.06)

0.64

2DP1 (n/%)

90 (77.5)

66 (100)

< 0.0001

3DP1 (n/%)

17 (14.6)

0

< 0.0001

3DP1*003 (n/%)

73 (62.9)

66 (100)

< 0.0001

KIR-aplotypes

   

HLA-A (n/%)

52 (44.8)

30 (45.4)

1.0

HLA-A+B (n/%)

62 (53.4)

37 (56.0)

0.76

HLA alleles

   

HLA-Bw4 T (n/%)

31 (26.7)

13 (19.6)

0.36

HLA-A-BW4 (n/%)

31 (26.7)

16 (24.2)

0.85

HLA-B-Bw4I (n/%)

10 (8.6)

43 (65.1)

< 0.0001

HLA-C1 (n/%)

38 (32.7)

26 (39.3)

0.420

HLA-C2 (n/%)

36 (31.03)

19 (28.7)

0.86

  1. KIR killer cell immunoglobulin-like receptor, HLA human leukocyte antigen