Skip to main content
Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain

Fig. 1

CCI induced neuropathic pain and increased the expression of p-ASK1 in the spinal cord of rats. a, b Mechanical allodynia and thermal hyperalgesia were significantly induced after CCI surgery (n = 8). c The expression of p-ASK1 and ASK1 were significantly increased at day 14 after CCI surgery in the spinal cord of rats. The lumbar spinal cords (L1–L6) were collected and analyzed 14 days after the CCI operation (n = 4). A significant difference was revealed following one-way ANOVA (*P < 0.05, **P < 0.01, ***P < 0.001 vs. control; Bonferroni post hoc tests)

Back to article page