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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

Fig. 4

MGL1 deficiency results in enhanced susceptibility to EAE. Wild-type (WT) and Clec10a−/− mice were immunized with MOG35–55 and examined for disease progression (a) and body weight changes (b). Two independent experiments with 6–8 mice per group are shown. Values represent the mean + SEM; *P < 0.05; **P < 0.01; ***P < 0.001 (one-tailed unpaired Student’s t test of the AUC); #P < 0.05; ##P < 0.01 (one-tailed Mann-Whitney of the mean maximum scores)

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