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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA

Fig. 6

Evaluation of inflammatory lesion load within the spinal cord of tolDC-treated and PBS-treated mice using ex vivo MRI imaging. PFA-fixed spinal cords from three representative mice per treatment group were analyzed using MRI for the presence of white matter hyperintense lesions. a Representative MRI of spinal cord with hyperintense white matter spots marked with a red arrow. Two representative axial slices per treatment group are shown. b The total number of hyperintense white matter spots along the entire spinal cord was quantified as a measure of lesion load in three mice per treatment group. Results are presented as individual scores for hyperintense spots with median

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Journal of Neuroinflammation

ISSN: 1742-2094