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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis

Fig. 3

Mdivi-1 inhibited phosphorylation of Drp1 (p-Drp1; ser616) in CD4+ T cells. Lumbar regions of spinal cords were harvested for immunostaining of CD4, p-Drp1 (ser616) on day 28 p.i. Representative microphotographs for CD4+ser616+ cells in spinal cords and quantitative analysis of area (polygon) of CD4+ser616+ cells in spinal cords. Data represent mean ± SEM (n = 5–8 each group). **P < 0.001. One representative of two experiments is shown

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