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Table 3 Results of statistical analysis of behavioral variables in elevated plus maze test

From: Peripheral and central compensatory mechanisms for impaired vagus nerve function during peripheral immune activation

Variable/time

1′

2′

3′

4′

5′

 Distance moved (m)

F(3,44) = 0.85, p = 0.475

F(3,44) = 0.77, p = 0.516

F(3,44) = 1.38, p = 0.261

F(3,44) = 4.66, p = 0.006

F(3,44) = 3.31, p = 0.029

 Velocity (cm/s)

F(3,44) = 0.92, p = 0.440

F(3,44) = 0.75, p = 0.526

F(3,44) = 1.38, p = 0.260

F(3,44) = 4.66, p = 0.006

F(3,44) = 3.29, p = 0.029

 Activity (mean %)

F(3,44) = 0.98, p = 0.412

F(3,44) = 1.11, p = 0.354

F(3,44) = 1.15, p = 0.339

F(3,44) = 2.73, p = 0.049

F(3,44) = 2.82, p = 0.049

 Enter to closed (f)

F(3,44) = 3.86, p = 0.016

F(3,44) = 0.81, p = 0.493

F(3,44) = 1.23, p = 0.309

F(3,44) = 0.83, p = 0.479

F(3,44) = 1.12, p = 0.351

 Open/closed time ratio

F(3,44) = 0.84, p = 0.482

F(3,44) = 1.23, p = 0.312

F(3,44) = 0.72, p = 0.547

F(3,44) = 2.91, p = 0.045

F(3,44) = 0.43, p = 0.731

Variable/group

SH NaCl

SH LPS

VG NaCl

VG LPS

 

 Distance moved (m)

F(4,55) = 6.04, p < 0.001

F(4,55) = 0.87, p = 0.491

F(4,55) = 0.22, p = 0.926

F(4,55) = 0.52, p = 0.714

 

 Velocity (cm/s)

F(4,55) = 5.99, p < 0.001

F(4,55) = 0.91, p = 0.466

F(4,55) = 0.22, p = 0.928

F(4,55) = 0,52, p = 0.724

 

 Activity (mean %)

F(4,55) = 5.84, p < 0.001

F(4,55) = 0.32, p = 0.864

F(4,55) = 0.49, p = 0.737

F(4,55) = 0.54, p = 0.708

 

 Enter to closed (f)

F(4,55) = 1.94, p = 0.116

F(4,55) = 1.89, p = 0.127

F(4,55) = 0,71, p = 0.585

F(4,55) = 1.52, p = 0.206

 

 Open/closed time ratio

F(4,55) = 1.32, p = 0.273

F(4,55) = 2.31, p = 0.072

F(4,55) = 1.19, p = 0.324

F(4,55) = 2.21, p = 0.078

 
  1. F—ANOVA test, standard font—statistical insignificant, bolded and italicized font—statistical significant. 1′,2′, 3′, 4′, 5′ —following minutes of the test, SH sham surgery, VG subdiaphragmatic vagotomy, NaCl single intraperitoneal vehicle injection, LPS single intraperitoneal LPS injection