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Table 1 List of 50 cell surface candidate genes specifically expressed by microglia or infiltrating macrophages

From: Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation

Microglia cell surface enriched genes

Macrophage cell surface enriched genes

Gene symbol

Gene name

Gene symbol

Gene name

Ecscr

Endothelial cell surface expressed chemotaxis and apoptosis regulator

Ecm1

Extracellular matrix protein 1

Scamp5

Secretory carrier membrane protein 5

Emb

Embigin

Ptprm

Protein tyrosine phosphatase, receptor type M

Slco3a1

Solute carrier organic anion transporter Family member 3a1

Kcnd1

Potassium voltage-gated channel subfamily D, member 1

Emp1

Epithelial membrane protein 1

Sdk1

Sidekick cell adhesion molecule 1

Ms4a7

Membrane spanning 4-domains A7

Clstn1

Calsyntenin-1

Gpr132

G protein-coupled receptor 132

Sgce

Sarcoglycan epsilon

Pdpn

Podoplanin

Slc12a2

Solute carrier family 12, member 2

Alcam

Activated Leukocyte Cell Adhesion Molecule

Cadm1

Cell adhesion molecule 1

Ms4a6d

Membrane-spanning 4-domains, subfamily A, member 6a

Sema4g

Semaphorin 4G

Msr1

Macrophage scavenger receptor-1

Pros1

Protein S

Kcnn4

Potassium calcium-activated channel subfamily N, member 4

Slco2b1

Solute carrier organic anion transporter family, member 2b1

Scarf1

Scavenger receptor class F member 1

Rtn4rl1

Reticulon 4 Receptor Like 1

Antxr2

Anthrax toxin receptor 2

Cmtm4

CKLF-like MARVEL transmembrane domain-containing protein 4

Fam26f

Calcium homeostasis modulator family, member 6

Fat3

Fat atypical cadherin 3

Ms4a8a

Membrane-spanning 4-domains subfamily A, member 8A

Smo

Smoothened homolog

Wfdc17

Activated macrophage/microglia WAP domain protein

Mrc2

Mannose receptor C type 2

Lilr4b

Leukocyte immunoglobulin-like receptor, subfamily B, member 4B

Jam2

Junctional adhesion molecule 2

Trem-1

Triggering receptor expressed on myeloid cells 1

Plxna4

Plexin A4

Gpr141

Probable G-protein coupled receptor 141

Slc46a1

Solute carrier family 46, member 1

Clec4e

C-type lectin domain family 4, member E

Agmo

Alkylglycerol monooxygenase (Tmem195)

Sirpb1a

SIRP-beta B-type

Gpr165

G protein-coupled receptor 165

Bst1

Bone marrow stromal cell antigen 1

Tmem204

Transmembrane Protein 204

Lilra6

Leukocyte immunoglobulin-like receptor subfamily A member 6

P2ry12

P2Y purinoceptor 12

Slfn4

Schlafen-4

  

Ifitm6

Interferon-induced transmembrane protein 6

  

Iqgap2

IQ motif-containing GTPase activating protein 2

  1. Cell surface localization of microglia- (left) or infiltrating macrophage- (right) specific gene products was determined using primary literature