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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis

Fig. 2

Decreased immune cell infiltration during EAE in RelBΔNP mice. EAE was induced in WT (RelBloxP/loxP) and RelBΔNP mice. Tissues were collected at the peak of disease. a Lumbar spinal cords (L2–L4) (left panels) were stained with hematoxylin and eosin. Quantification of immune cells infiltration into peripheral regions of spinal cords. n = 6, T test: F = 2.024, p = 0.0226). b Flow cytometry was conducted to quantify the indicated cells in the brains. n = 4 mice per group. T tests: CD45 (F = 6.486, p = 0.041); Cd11b+ (F = 1.956, p = 0.014); CD11b+CD45low (F = 3.497, p = 0.026). c Expression of the cytokines was examined by qPCR in lumbar spinal cords. n = 3–5 mice per group. IL-10, two-way ANOVA (F = 12.84, p = 0.004), Sidak’s test (p = 0.005)

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