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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Depletion of regulatory T cells increases T cell brain infiltration, reactive astrogliosis, and interferon-γ gene expression in acute experimental traumatic brain injury

Fig. 2

DTx-mediated depletion of Tregs in DEREG mice. a FACS plot examples of blood lymphocyte gates from naive DEREG mice (control) or DTx-treated DEREG mice showing the lymphocyte populations for naive DEREG mice (control) and for DEREG + DTx at 5 days after the last DTx administration. b FACS plot examples showing CD4+ lymphocytes vs. FoxP3-GFP+ Tregs in blood samples from DEREG control mice and DEREG DTx-treated mice. c Histogram showing depletion of FoxP3-GFP+ Tregs in DTx-treated DEREG mice. Data represent mean ± SEM (n = 5–10) and statistical significance was calculated by Mann-Whitney U test (***p < 0.001)

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