Fig. 3From: Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s diseaseCorrelations between KP metabolites and NFL in participants with low NAL (a) and high NAL (b). Plasma neurofilament light chain (NFL) correlated with the kynurenine to tryptophan ratio (K/T) and other kynurenine pathway (KP) metabolites, namely kynurenine (KYN), kynurenic acid (KA), and anthranilic acid (AA) in participants with low NAL. Plasma NFL correlated with the K/T and other kynurenine pathway KP metabolites, namely KYN, KA, AA, 3-HK, and QA. Analyses were carried out using Pearson’s correlation coefficient. Log transformed plasma NFL and KP analyte concentrations have been presentedBack to article page