Fig. 2
From: Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain
Carrageenan injection into the prostate induced chronic prostatitis and mechanical hyperalgesia. a Images of HE staining showing lots of inflammatory cells infiltrated in the prostate stroma 5 weeks after carrageenan injection. b Images of HE staining showing no inflammatory cell infiltration was observed in the prostatic stroma in the saline-treated group. Top: low-magnification image, bottom: enlarged images from the box. Scales, 100 μm. c Carrageenan-induced mechanical allodynia in the lower abdominal area. BL, baseline. *P < 0.05, vs. BL (baseline). Two-way ANOVA, followed by post hoc Bonferroni test. n = 5 mice in each group. All data are expressed as mean ± S.E.M.