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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Changes in cytokine and chemokine profiles in mouse serum and brain, and in human neural cells, upon tick-borne encephalitis virus infection

Fig. 3

Growth of tick-borne encephalitis virus (TBEV) and cytokine/chemokine production in SK-N-SH and HBCA cells. SK-N-SH or HBCA cells were infected with TBEV (m.o.i. = 1), and then cell-free culture supernatants were collected at given time intervals. Supernatants were analyzed for virus titer using a plaque assay or analyzed for cytokine/chemokine concentration. TBEV growth in SK-N-SH cells (a) and HBCA cells (b). Supernatants from TBEV-infected, uninfected, and mock-infected (UV-inactivated virus) SK-N-SH cells (c) and HBCA cells (d) were analyzed for levels of multiple cytokines, chemokines, and growth factors using the Human Cytokine Magnetic 30-Plex Panel for the Luminex platform. Asterisks indicate statistically significant differences compared to uninfected controls

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Journal of Neuroinflammation

ISSN: 1742-2094