Fig. 4
From: Tempol improves neuroinflammation and delays motor dysfunction in a mouse model (SOD1G93A) of ALS
Images of astrocyte activation in the anterior horn of the spinal cord. The immunolabeling of GFAP was quantified in the early symptomatic phase (week 14) (a, c, e, g) and at the end stage (b, d, f, h). Scale bar: 50 μm. Graphical representation of percent GFAP expression at 14 weeks (i) and end-stage (j) of ALS. Data were analyzed by one-way ANOVA, followed by post hoc Bonferroni test. ***p < 0.0001 vs NTG; ###p < 0.0001 vs vehicle; &&p < 0.001 vs riluzole