Fig. 5
From: Tempol improves neuroinflammation and delays motor dysfunction in a mouse model (SOD1G93A) of ALS
Images show microglial activation in the anterior horn of the spinal cord. The immunolabeling of Iba1 was quantified in the early symptomatic phase (week 14) and at the end stage (a–p). Scale bar: 50 μm. Graphical representation of percent Iba 1 expression at 14 weeks (m) and end-stage (n, ventral horn), (o, intermediate region), (p, dorsal horn) of ALS. Data were analyzed by one-way ANOVA, followed by post hoc Bonferroni test. ***p < 0.0001 vs NTG; #p < 0.05, ##p < 0.001, and ###p < 0.0001 vs vehicle; &p < 0.05, &&p < 0.001, and &&&p < 0.0001 vs riluzole