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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Human bone marrow mesenchymal stem cell-derived extracellular vesicles attenuate neuroinflammation evoked by focal brain injury in rats

Fig. 7

Human bone marrow mesenchymal stem cells (hBM-MSCs) or their extracellular vesicles (EVs) transplanted intra-arterially alleviate CD45RA+ cells in the rat brain evoked by focal brain injury. a Representative images of CD45RA staining in the rat brain of control rats, focal brain injured rats left intact, and those receiving hBM-MSC or EV transplantation. Scale bars 20 μm. b Quantitative analysis of the host cells positive for CD45RA observed in the rat brains of focal brain injured rats 24 h, 3 days, and 7 days after hBM-MSC or EV transplantation versus untreated or control rats. All data reflect mean ± SD from 6 animals. *p < 0.1; **p < 0.01; ***p < 0.001; ****p < 0.0001

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Journal of Neuroinflammation

ISSN: 1742-2094