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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage

Fig. 4

mRNA analysis of LPS-stimulated MΦ monocytes/macrophages treated with EphA4 peptide inhibitors. Quantified mRNA expression of pro-inflammatory genes Epha4 (a), Il6 (b), Mcp1 (c), TNF (d), Cxcl1 (e), and Il12 (f) and of pro-resolving genes Il10 (g), Angpt2 (h), Arg1 (i), and Tgfβ (j) following 4 h LPS stimulation of cultured MΦ monocytes/macrophages in the presence and absence of VTM-EEKK and KYL compared to vehicle control. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to the corresponding control PBS treatment. n = 3 biological replicates

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