Fig. 3
11C-PBR28 autoradiography with corresponding immunohistochemistry and histology of fDTH-EAE rat brains in acute and chronic phases with quantitative data. a Representative ex vivo 11C-PBR28 autoradiographs, anti-CD-68 immunohistochemical staining, and H&E and Luxol Fast Blue (LFB) histological staining. The low-power scale bar is 2 mm, and the high-power scale bar is 50 μm. Quantification of b 11C-PBR28 autoradiography data and c demyelination from LFB staining. Differences between day 14 and day 90 measures were not statistically significant (P > 0.05). Error bars denote standard deviation. White asterisk in the H&E staining denotes the intracranial injection site to induce EAE