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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Apelin-13/APJ system attenuates early brain injury via suppression of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation and oxidative stress in a AMPK-dependent manner after subarachnoid hemorrhage in rats

Fig. 2

Effects of exogenous apelin-13 on neurological functions, brain edema, and BBB leakage. a Representative pictures of brains in Sham and SAH groups. b SAH grade of each group. c The quantification of brain water content 24 h after SAH. d The quantification of Evans blue dye extravasation 24 h after SAH (n = 6 for each group). e, f Modified Garcia score and beam balance score; the effects of apelin-13 on long-term neurobehavioral outcomes after SAH. h Escape latency and i swim distance of Morris water maze on days 21 to 25 after SAH. j Probe quadrant duration. The bars represent the mean ± SD. *P < 0.05 versus sham, #P < 0.05 versus SAH + vehicle at 24 h, n = 10 per group

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Journal of Neuroinflammation

ISSN: 1742-2094