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Table 1 The plasma levels of TNF-α, IL-1β and IL-6 in the control, LPS and LPS with pentoxifylline or minocycline treatment groups

From: Anti-neuroinflammation ameliorates systemic inflammation-induced mitochondrial DNA impairment in the nucleus of the solitary tract and cardiovascular reflex dysfunction

(pg/mL)

C

LPS

LPS+PTX

LPS+mino

TNF-α

7.92 ± 1.6

29.21 ± 3.1**

25.46 ± 9.6*

19.35 ± 3.8

IL-1β

19.08 ± 2.2

49.39 ± 4.1**

37.33 ± 9.4

38.20 ± 4.4*

IL-6

2659 ± 62.5

2946 ± 3.0

3176 ± 168.8

2980 ± 228.8

  1. Values are the mean ± SEM of 12 to 16 animals in each group. *P < 0.05, **P < 0.01 versus the vehicle control group in the post hoc Tukey’s multiple range analysis. C control, L LPS, lipopolysaccharides, PTX pentoxifylline, mino minocycline
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Journal of Neuroinflammation

ISSN: 1742-2094