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Table 1 The plasma levels of TNF-α, IL-1β and IL-6 in the control, LPS and LPS with pentoxifylline or minocycline treatment groups

From: Anti-neuroinflammation ameliorates systemic inflammation-induced mitochondrial DNA impairment in the nucleus of the solitary tract and cardiovascular reflex dysfunction

(pg/mL) C LPS LPS+PTX LPS+mino
TNF-α 7.92 ± 1.6 29.21 ± 3.1** 25.46 ± 9.6* 19.35 ± 3.8
IL-1β 19.08 ± 2.2 49.39 ± 4.1** 37.33 ± 9.4 38.20 ± 4.4*
IL-6 2659 ± 62.5 2946 ± 3.0 3176 ± 168.8 2980 ± 228.8
  1. Values are the mean ± SEM of 12 to 16 animals in each group. *P < 0.05, **P < 0.01 versus the vehicle control group in the post hoc Tukey’s multiple range analysis. C control, L LPS, lipopolysaccharides, PTX pentoxifylline, mino minocycline