Fig. 1

PGRN expression is enhanced in SCI. a, b Representative Western blotting of PGRN at different time points after SCI (a); Quantification of Western Blots with Image J (n = 3 per group) (b). One-way ANOVA and Turkey’s post hoc test were used. *p < 0.05, **p < 0.01 compared with sham group. c, d The specificity of the PGRN antibodies was confirmed by Western blotting (c) and immunofluorescence (d) in Grn^−∕− mice at 7 days after SCI