Table 2 Gene ontological analysis: downregulation (APP/PS1 Tg/sEH−∕− vs. APP/PS1 Tg)
From: Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer’s disease
Biological process | Count | P value |
|---|---|---|
Positive regulation of protein complex disassembly | 4 | 3.01E−05 |
Cellular macromolecular complex assembly | 12 | 4.62E−05 |
Small GTPase-mediated signal transduction | 13 | 4.81E−05 |
Molecular functions | ||
GTP binding | 22 | 4.31E−09 |
Guanyl nucleotide binding | 22 | 6.72E−09 |
Guanyl ribonucleotide binding | 22 | 6.72E−09 |
KEGG pathway | ||
Ribosome | 9 | 1.42E−04 |
FcγR-mediated phagocytosis | 7 | 6.97E−03 |
AD | 9 | 1.36E−02 |