Fig. 3

Real-time RT-PCR gene expression of TNFR1 (a) and TNFR2 (b) in the precentral gyrus, both grey matter lesion (GML) and normal appearing grey matter (NAGM), of 10 F+ and 10 F− SPMS cases compared with 10 controls (***p < 0.001, **p < 0.01, *p < 0.05). Protein expression of TNFR1 (c) and TNFR2 (d) in precentral gyrus, both grey matter lesion (GML) of 10 F+ and 10 F− SPMS cases compared with 5 controls (**p < 0.01, *p < 0.05). For each statistical comparison, the p value, obtained by non-parametric Mann-Whitney test, has been reported