Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Recombinant CC16 inhibits NLRP3/caspase-1-induced pyroptosis through p38 MAPK and ERK signaling pathways in the brain of a neonatal rat model with sepsis

Fig. 4

The expression of NLRP3 and caspase-1 in each group at different time points. a, b NLRP3 and caspase-1 in the cortex harvested at specific time points after CLP. The protein levels were normalized to those of tubulin protein and are shown as relative arbitrary units. c Fluorescence of NLRP3 and caspase-1 in the cortex at specific time points after CLP. Three-color staining for anti-NLRP3 antibody (green), anti-caspase-1 (red), and nucleus (blue), the protein volume and coincidence rate are represented by histograms. Scale bar = 40 μm. Values are expressed as mean ± SEM (n = 6 in each group; *P < 0.05 vs. sham group, in the corresponding group)

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094