Systemic activation of NLRP3 inflammasome and plasma α-synuclein levels are correlated with motor severity and progression in Parkinson’s disease

Table 1 Clinical characteristics of study participants

Variables	PD patients (n = 43)	Healthy control (n = 24)	p value
Gender (female/male)	19/24	11/13	0.549^a
Age (years)	58.40 ± 1.37	57.92 ± 1.58	0.695^b
Disease duration (years)	2.27 ± 0.34	N.A.	N.A.
H-Y	1.93 ± 0.11	N.A.	N.A.
UPDRS part I	8.72 ± 0.76	N.A.	N.A.
UPDRS part III	31.35 ± 2.05	N.A.	N.A.

Numbers are expressed as mean ± SEM
N.A. not available, PD Parkinson’s disease, H-Y Hoehn-Yahr staging scale, UPDRS Unified Parkinson’s Disease Rating Scale
^aFisher’s exact test
^bMann-Whitney test

ISSN: 1742-2094