Fig. 4

Genetic KCa3.1 deletion and pharmacological blockade with senicapoc attenuated MPTP-induced ER stress. a, d Western blot analysis of GRP78 and CHOP protein levels in SNpc. b, c, e, f Data are presented as the mean ± SEM (n = 5–6). Western blot was repeated three times and showed similar results. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs. control or WT group mice; *p < 0.05, ***p < 0.001 vs. MPTP or WT+MPTP group mice. One-way ANOVA followed by Dunnett’s multiple comparison test. WT, wild-type