Table 1 Comparison of baseline characteristics and levels of cytokines between good and poor outcome groups

Age, median (IQs)

66 (58–75)

72 (63–81)

<0.01

Female, n (%)

53 (38.7)

49 (44.1)

0.75

Hypertension, n (%)

104 (75.9)

90 (81.1)

0.33

Diabetes mellitus, n (%)

35 (25.6)

35 (31.5)

0.30

Atrial fibrillation, n (%)

40 (29.2)

31 (27.9)

0.83

Myocardial infarction, n (%)

17 (12.4)

17 (15.3)

0.51

Previous stroke, n (%)

14 (10.2)

16 (14.4)

0.31

Current smoking, n (%)

37 (27.0)

27 (24.3)

0.63

NIHSS score on admission, median (IQs)

6 (4–13)

15 (7–19)

<0.01

Thrombolysis, n (%)

77 (56.2)

61 (55.0)

0.84

Thrombectomy, n (%)

39 (28.5)

26 (23.4)

0.37

Etiology

0.17

 Large vessel disease, n (%)

29 (21.2)

37 (33.3)

 Small vessel disease, n (%)

9 (6.6)

4 (3.6)

 Cardioembolic, n (%)

44 (32.1)

29 (26.1)

 Undetermined, n (%)

49 (35.8)

39 (35.1)

 Other, n (%)

6 (4.4)

2 (1.8)

 IL-12p70, pg/ml, median (IQs)

5.6 (1.7–11.0)

3.0 (0.0–5.2)

<0.01

 IL-10, pg/ml, median (IQs)

44.4 (32.0–69.3)

65.6 (40.4–89.4)

<0.01

 IL-6, pg/ml, median (IQs)

11611 (8279–16298)

11534 (8013–17757)

0.96

 IL-1β, pg/ml, median (IQs)

1611 (1101–2313)

1323 (797–2095)

0.01

 IL-8, pg/ml, median (IQs)

1528 (953–2276)

2256 (1237–3459)

<0.01

 TNFα, pg/ml, median (IQs)

2570 (1785–3793)

2071 (1518–2835)

<0.01

 IP-10, pg/ml, median (IQs)

474 (25–832)

288 (138–534)

<0.01

 IL-6, pg/ml, median (IQs)

3.2 (1.9–6.5)

8.9 (4.6–25.2)

<0.01