The association between serum adipocyte fatty acid–binding protein and 3-month disability outcome after aneurysmal subarachnoid hemorrhage

Table 5 Multivariate logistic regression analysis for mortality according to FABP4 quartiles

FABP4^a	Death/N (%)	Crude OR (95% CI), P^#	Multivariable-adjusted^b, P^#
Quartile 1	4/107 (3.7)	Reference	Reference
Quartile 2	10/105 (9.5)	2.71 (0.82–8.93), 0.090	–
Quartile 3	13/102 (12.7)	3.76 (1.18–11.95), 0.017	2.59 (1.42–6.11), 0.042
Quartile 4	25/104 (24.0)	8.15 (2.73–24.37), < 0.001	4.55 (2.54–9.13), < 0.001
Elevated vs. normal	38/206 vs. 14/212	3.20 (1.68–6.11), < 0.001	2.26 (1.30–5.77), 0.011

^aFABP4 in quartile 1 (< 12.5 ng/ml), quartile 2 (12.5–18.2 ng/ml), quartile 3 (18.3–24.9 ng/ml), and quartile 4 (> 24.9 ng/ml). Elevated FABP4 level was defined as ≥ 24.9 ng/ml (3rd quartile)
^bAdjusted for those significant risk factors which confirmed in the univariate analysis (Table 2), including age, hypertension, cardiovascular comorbidities, a history of nicotine abuse, surgical clip, coiling, complications in the study, H-H score, aneurysm size > 10 mm, APACHE-II score, IVH sum score, hydrocephalus, cerebral vasospasm, DCI, glucose, and CRP
^#P value for the trend < 0.001
OR odds ratio, CI confidence interval, CRP C-reactive protein, APACHE-II 5 Acute Physiology and Chronic Health Evaluation II, IVH intraventricular hemorrhage, DCI delayed cerebral ischemia, ICH intracerebral hemorrhage, CRP C-reactive protein, TCD transcranial Doppler, H-H Hunt–Hess

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