Fig. 2

Adjuvant therapy with vitamin B₁₂ attenuates apoptosis in the granular layer of the hippocampal dentate gyrus of infant rats with BM. a Nissl-stained histological section showing the hippocampal dentate gyrus (× 100) of an infected animal treated with placebo. The detail shows an amplified section of the lower blade of the granular layer (× 400). Barr = 50 μm. b Apoptotic scores. Horizontal bars represent means. The effects of the BM and adjuvant treatment with vitamin B₁₂ were compared using a 2-way ANOVA (Bonferroni post hoc test). P values in tables below the graphs refer to the 2-way ANOVA and asterisks refer to the post hoc test. **P < 0.01; ***P < 0.001