Fig. 3
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12974-020-01763-y/MediaObjects/12974_2020_1763_Fig3_HTML.png)
Effects of BM and adjuvant therapy with vitamin B12 on a SAM and b SAH concentrations and c SAM:SAH ratio in the hippocampus. Horizontal bars represent means. The effects of the BM and the vitamin B12 adjuvant treatment were compared using a 2-way ANOVA (Bonferroni post hoc test). P values in tables below the graphs refer to the 2-way ANOVA and asterisks refer to the post hoc test. *P < 0.05; **P < 0.01. SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine