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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Vitamin B12 is neuroprotective in experimental pneumococcal meningitis through modulation of hippocampal DNA methylation

Fig. 6

Effects of BM and adjuvant therapy with vitamin B12 on Dnmt3a and Tet1 expression in the hippocampus. Dnmt3a and Tet1 mRNA levels in the hippocampus were assessed by the 2−ΔΔCt method. Ppia was used as a reference gene. The effects of the BM and vitamin B12 were compared using a 2-way ANOVA (Bonferroni post hoc test). P values in tables below the graphs refer to the 2-way ANOVA and asterisks refer to the post hoc test. *P < 0.05; **P < 0.01; ***P < 0.001

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