Fig. 4
From: DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke
DJ-1 regulated SHP-1-TRAF6 and NLRX1-TRAF6 interactions after cerebral I/R injury. a, c Immunoprecipitation and immunoblot analyses of NLRX1-TRAF6 in rats. NLRX1 disassociated from TRAF6 after MCAO/R, and NLRX1 interacted with TRAF6 after treatment with DJ-1 siRNA. b, d Immunoprecipitation and immunoblot analyses of SHP-1-TRAF6 in rats. SHP-1 was associated with TRAF6 in the MCAO group, and SHP-1 disassociated from TRAF6 after treatment with DJ-1 siRNA. n = 6 per group