Fig. 6

MiR-9-5p modified BMSCs regulated expressions of REST and MOR in ipsilateral dorsal root ganglion (DRG) of sarcoma-inoculated mice. a MiR-9-5p modified BMSCs reduced REST mRNA level at day 21 post operation. b MiR-9-5p modified BMSCs enhanced MOR mRNA level at day 21 post operation. c Accordingly, MiR-9-5p modified BMSCs reduced REST protein expression but enhanced MOR protein expression at 21 days post operation. d Quantification of protein expression presented in c. qRT-PCR was used to evaluate mRNA level and western blotting was used to evaluate protein expression. In each group, n = 6. Mean ± SD is used to present all data. *p < 0.05, **p < 0.01