Fig. 3
Effect of BCCAO with/without Aβ1-40 on oxidative stress markers. a Superoxide anion production in the hippocampus 8 days after injection determined by DHE staining. Representative photographs in each group were from the same location in the DG area, × 200 magnification. Scale bar = 250 μm. n = 6 for each group in WT and smAT2, respectively. b NADPH oxidase activity in the hippocampus 4 days after injection determined by luminescence assay. Expressions of NADPH oxidase subunits (c) and superoxide dismutase (SOD) (d) in the hippocampus 3 weeks after injection were determined by real-time RT-PCR. n = 9 for each group in WT; n = 6 for each group in smAT2. *P < 0.05, †P < 0.01 vs. PBS, BCCAO (−), respectively