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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

Fig. 1

C/EBPβ levels are increased in the astroglia and decreased in neurons in HAND cases. a Vibratome sections of frontal cortex tissues from HIV CN and HAND cases immunolabeled for C/EBPβ. b Vibratome sections from the frontal cortex from HIV CN and HAND cases double immunolabeled for GFAP (green) and C/EBPβ (red). c The percent of C/EBPβ colocalizing with GFAP for CN versus HAND cases. d Double immunolabeling was for MAP2 (green) and C/EBPβ. e Percent colocalization comparing CN and HAND cases. f RNA expression of C/EBPβ normalized to GAPDH plotted by neurocognitive status. g Western blot for C/EBPβ and ACTB using lysates of frontal cortex tissues. h Band intensities for C/EBPβ plotted by neurocognitive status after normalization to ACTB. Statistical significance was determined by an unpaired t test when comparing two groups and by one-way ANOVA when comparing more than two groups (*p < 0.05, **p < 0.01)

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Journal of Neuroinflammation

ISSN: 1742-2094