Fig. 3

Effects of JWH-133 pretreatment on the protein expression of MyD88/NF-κB and MMP9 activity after I/R injury in the spinal cord tissue. a Protein expression of MyD88, NF-κB p-p65, and NF-κB p65 at day 2 after injury. JWH-133 treatment reduced the expression of MyD88 and NF-κB p-p65 comparing with I/R group. b MMP9 activity at day 2 after injury. The MMP9 activity of JWH group was obviously less than that of I/R group. All results are represented as mean ± SEM (n = 5). *P < 0.05 vs. sham group; #P < 0.05 vs. I/R group