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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Normalization of magnesium deficiency attenuated mechanical allodynia, depressive-like behaviors, and memory deficits associated with cyclophosphamide-induced cystitis by inhibiting TNF-α/NF-κB signaling in female rats

Fig. 8

L-TAMS inhibited the TNF-α, p-p65, and IL-1β increase observed in the SDH and hippocampus. a–c L-TAMS inhibited the increased expression of TNF-α, p-p65, and IL-1β observed in the SDH of cystitis rats harvested on day 20 after the first CYP injection. d–f The increased expression of TNF-α, p-p65, and IL-1β in the hippocampus of cystitis model rats was also attenuated by L-TAMS treatment on day 20. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. Veh group, #P < 0.05, ##P < 0.01, and ###P < 0.001 vs. CYP group. All data were analyzed by one-way ANOVA followed by the Tukey post hoc test

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Journal of Neuroinflammation

ISSN: 1742-2094