Fig. 1

PKO mice show enlarged hematoma size and increased neurological deficit score after ICH. a Representative images of hematoxylin-stained control and PKO brains from sham group and at D2, D5, and D14 after ICH. Dashed lines mark injury areas. b Quantification of injury volume in control and PKO mice. *p < 0.05 and **p < 0.01, compared to controls at the same time points (Student’s t test), n = 6. c Neurological deficit score in control and PKO mice from sham group and at D1, D2, D3, D5, D7, D10, and D14 after ICH. *p < 0.05 and **p < 0.01, ***p < 0.001, compared to controls at the same time points (Student’s t test), n = 5–15 (n = 15 for D1–D2, n = 12–14 for D3–D5, and n = 5 for sham and D7–D14). Data are shown as mean ± SD